Thermo Fisher Scientific TAS2R4 Polyclonal Antibody
TAS2R4 단백질을 인식하는 Rabbit Polyclonal 항체로 Western blot에 적합. Human, Mouse, Rat 시료 반응. 합성 펩타이드 면역원 사용. 액상 형태, 1 mg/mL 농도, -20°C 보관. 연구용으로만 사용.
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Applications
- Western Blot (WB): 1:1,000–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthesized peptide derived from human TAS2R4 (amino acids 61–85, UniProt ID: Q9NYW5-1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2692011 |
Product Specific Information
Predicted to react with Mouse and Rat samples.
Target Information
The TAS2R4 gene encodes a member of the G protein-coupled receptor (GPCR) superfamily, specifically expressed in taste receptor cells of the tongue and palate epithelia. This intronless gene encodes a 7-transmembrane receptor protein functioning as a bitter taste receptor.
It is clustered with three other candidate taste receptor genes on chromosome 7 and is genetically linked to loci influencing bitter perception. TAS2R4 acts as a gustducin-coupled receptor for denatonium and N(6)-propyl-2-thiouracil, mediating perception of bitter compounds in the oral cavity and gastrointestinal tract.
The receptor signals through PLCB2 and TRPM5, and is expressed in gustducin-positive taste receptor cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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