Thermo Fisher Scientific Sortilin Polyclonal Antibody
Sortilin 단백질을 인식하는 Rabbit Polyclonal 항체. Western blot 및 IHC(P) 검증 완료. 항원 친화 크로마토그래피로 정제된 액상 항체로, 4℃ 단기 보관 및 -20℃ 장기 보관 권장. 연구용으로만 사용 가능.
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- PA5110713
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- pk
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:20–1:50 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human Sortilin (Product #RP-88683) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2856124 |
Product Specific Information
Immunogen sequence:
LERNCEEKDY TIWLAHSTDP EDYEDGCILG YKEQFLRLRK SSVCQNGRDY VVTKQPSICL CSLEDFLCDF GYYRPENDSK CVEQPELKGH DLEFCLYGRE EHLTTNGYRK IPGDKCQGGV NPVREVKD
Target Information
Sortilin functions as a sorting receptor in the Golgi compartment and as a clearance receptor on the cell surface.
It is required for protein transport from the Golgi apparatus to the lysosomes via an M6PR-independent pathway and to the endosomes.
Sortilin promotes neuronal apoptosis by mediating endocytosis of proBDNF and proNGFB and also acts as a receptor for neurotensin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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