Thermo Fisher Scientific CCR1 Monoclonal Antibody (8E10F9)
CCR1 단백질을 인식하는 마우스 단클론 항체로, Western blot, Flow cytometry, ELISA에 사용 가능. 인간 시료에 반응하며 Protein G로 정제된 액상 항체. 염증 및 면역세포 이동 연구에 적합. 연구용으로만 사용.
- 카탈로그번호
- MA531672
- 판매단위
- pk
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Flow Cytometry (Flow) | 1:200–1:400 |
| ELISA | 1:10,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 8E10F9 |
| Immunogen | Purified recombinant fragment of human CD191 expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2787296 |
Product Specific Information
MA5-31672 has been tested in indirect ELISA.
Target Information
Chemokines play important roles in inflammation and are critical for the recruitment of effector immune cells to sites of infection. Chemokines activate leukocytes by binding to G protein-coupled receptors. The chemokine receptor subtypes can be divided into two major groups, CXCR and CCR, based on their ligand classes.
CCR1, one of the CCR receptors, is expressed on neutrophils, monocytes, lymphocytes, and eosinophils. It binds macrophage-inflammatory protein (MIP-1α), eotaxin, and several related chemokines.
Mice lacking CCR1 show defects in neutrophil trafficking and proliferation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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