Thermo Fisher Scientific CBR4 Polyclonal Antibody
인간 및 랫트 반응성의 Rabbit Polyclonal CBR4 항체로, Western blot과 ELISA에 적합합니다. 미토콘드리아 지방산 생합성 연구에 활용되며, 고순도 친화 크로마토그래피 정제 및 안정적 액상 형태로 제공됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:200–1:2,000
ELISA
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1–237 of human CBR4 (NP_1161722) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.47 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2806442 |
Product Specific Information
Immunogen sequence:
MDKVCAVFGG SRGIGRAVAQ LMARKGYRLA VIARNLEGAK AAAGDLGGDH LAFSCDVAKE HDVQNTFEEL EKHLGRVNFL VNAAGINRDG LLVRTKTEDM VSQLHTNLLG SMLTCKAAMR TMIQQQGGSI VNVGSIVGLK GNSGQSVYSA SKGGLVGFSR ALAKEVARKK IRVNVVAPGF VHTDMTKDLK EEHLKKNIPL GRFGETIEVA HAVVFLLESP YITGHVLVVD GGLQLIL
Positive Samples: Jurkat, MCF7, 293T
Cellular Location: Mitochondrion matrix
Target Information
The heterotetramer with HSD17B8 has NADH-dependent 3-ketoacyl-acyl carrier protein reductase activity, playing a role in mitochondrial fatty acid biosynthesis.
Within the heterotetramer, HSD17B8 binds NADH; CBR4 binds NADPD.
The homotetramer has NADPH-dependent quinone reductase activity.
Both homotetramer and heterotetramer have broad substrate specificity and can reduce 9,10-phenanthrenequinone, 1,4-benzoquinone and various other o-quinones and p-quinones (in vitro).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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