Thermo Fisher Scientific RNF14 Monoclonal Antibody (OTI1C9), TrueMAB
RNF14 단백질을 인식하는 Mouse IgG2a 단클론 항체로, WB 및 IHC(P) 응용에 적합합니다. 인간 및 생쥐 반응성을 가지며, 액상 형태로 1 mg/mL 농도입니다. Affinity chromatography로 정제되었으며, 연구용으로만 사용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1C9 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–220 of human RNF14 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The protein encoded by this gene contains a RING zinc finger motif involved in protein-protein interactions. It interacts with androgen receptor (AR) and may function as a coactivator inducing AR target gene expression in prostate tissue. A dominant negative mutant of this gene inhibits AR-mediated growth of prostate cancer. This protein also interacts with class III ubiquitin-conjugating enzymes (E2s) and may act as a ubiquitin-ligase (E3) in ubiquitination of certain nuclear proteins. Five alternatively spliced transcript variants encoding two distinct isoforms have been reported.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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