Thermo Fisher Scientific ZNF322A Polyclonal Antibody
Human ZNF322A 단백질을 인식하는 Rabbit Polyclonal Antibody로 Western Blot과 IHC에 적합. C-terminal 합성 펩타이드로 면역원 제작. 높은 종 간 상동성 및 핵/세포질 발현 검출에 유용. 연구용으로만 사용 가능.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.2–1 µg/mL |
| Immunohistochemistry (IHC) | 5 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the C-terminal of human ZNF322A (aa 353–402) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2607212 |
Product Specific Information
Peptide sequence:
YTVCDKSFHQ SSALLQHQTV HIGEKPFVCN VSEKGLELSP PHASEASQMS
Sequence homology:
Cow: 85%; Dog: 100%; Goat: 92%; Horse: 100%; Human: 100%; Mouse: 79%; Pig: 92%; Rabbit: 92%; Rat: 79%
Target Information
ZNF322 contains four exons and spans 23.2 kb in chromosome 6p22.1 region, transcribing a 2.7 kb mRNA that encodes a protein with 402 amino acid residues.
Through northern blot analysis, ZNF322 was shown to be expressed in all human tissues examined at adult and embryonic stages (80 days to 24 weeks).
When ZNF322 was overexpressed in COS-7 cells, ZNF322-EGFP fusion protein was detected in the nucleus and cytoplasm. Reporter gene assays show that ZNF322 acts as a transcriptional activator.
Overexpression of ZNF322 in COS-7 cells activates transcriptional activity of SRE and AP-1, suggesting ZNF322 is a zinc-finger transcription factor that positively regulates gene transcription via MAPK signaling pathways.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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