Thermo Fisher Scientific TRPM2 Polyclonal Antibody
TRPM2 단백질을 인식하는 Sheep 유래 Polyclonal Antibody로, Rat 시료에 반응합니다. Western blot과 IHC에 사용 가능하며, 합성 펩타이드(aa 1100–1150)를 면역원으로 제작되었습니다. 연구용으로만 사용되며, 장기보관 시 -20°C에서 보관합니다.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:300–1:2,000 | - |
| Immunohistochemistry (IHC) | 1:300–1:2,000 | - |
| Miscellaneous PubMed (Misc) | - | View 2 publications |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Rat |
| Published Species | Not Applicable |
| Host / Isotype | Sheep / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from aa region 1100–1150 of rat TRPM2 conjugated to blue carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 100 µL of sterile water.
- Centrifuge to remove any insoluble material.
- Specificity: TRPM2.
Target Information
TRPM2 belongs to the ion transport protein family, which includes sodium, potassium, and calcium ion channels. This family is characterized by proteins possessing six transmembrane helices, where the last two helices flank a loop determining ion selectivity.
TRPM2 is activated by oxidative stress and confers susceptibility to cell death. It functions as a calcium-permeable cation channel regulated by free intracellular ADP-ribose. Several alternatively spliced transcript variants of the TRPM2 gene have been described, but their full-length nature is not known.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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