Thermo Fisher Scientific PIK3C2G Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000

-

Immunohistochemistry (IHC)

-

View 1 publication 1 publication

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:100

-

Product Specifications

Species Reactivity

Human

Published species

Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

KLH conjugated synthetic peptide between 93-123 amino acids from the N-terminal region of human PI3KC2G if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:PIK3C2G,uniProtId:O75747-1,ncbiNodeId:9606,antigenRange:93-123,antigenLength:1445,antigenImageFileName:PA5-15239_PIK3C2G_O75747-1_Rabbit.svg,antigenImageFileNamePDP:PA5-15239_PIK3C2G_O75747-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

2 mg/mL

Purification

Size-exclusion - Dialysis, Ammonium sulfate precipitation

Storage buffer

PBS, pH 7.4

Contains

0.09% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2165106

Target Information

PIK3C2G lipid kinase belongs to the phosphoinositide 3-kinase (PI3K) family which play major roles in signaling pathways and are involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. PIK3C2G contains a lipid kinase catalytic domain as well as a C-terminal C2 domain, a characteristic of class II PI3-kinases that act as calcium-dependent phospholipid binding motifs which mediate translocation of proteins to membranes, and may also mediate protein-protein interactions. The N-terminal region of PIK3C2G and the C-terminal C2 domain are required for enzymatic activity. The PI 3-kinase C2gamma gene encodes a 1,050 amino acid polypeptide with 36% identity to human PI 3-kinase C2alpha. Research indicates that PI 3-kinase C2gamma can block the growth of human colon cancer cells.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.