Thermo Fisher Scientific Phospho-TGFBR1 (Thr204) Polyclonal Antibody
인간, 생쥐, 랫트에서 인산화된 TGFBR1(Thr204)을 특이적으로 검출하는 폴리클로날 항체. Western blot에 적합하며, 고순도 친화 크로마토그래피 정제 제품. 액상 형태로 제공되며, -20°C에서 안정적으로 보관 가능.
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Applications
- Western Blot (WB)
Tested Dilution: 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human TGFBR1 (Phospho-Thr204) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2662826 |
Product Specific Information
Phospho-TGFBR1 (Thr204) Polyclonal Antibody detects endogenous levels of TGFBR1 only when phosphorylated at Thr204.
Target Information
TGFBR1 is a transmembrane serine/threonine kinase in the TGFBR1 superfamily, which includes ACVRs and BMPRs.
Upon binding TGF-β, TGFBR2 dimerizes with and activates TGFBR1 via phosphorylation, leading to downstream phosphorylation of SMADs by TGFBR1.
TGFBR1 forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the signal from the cell surface to the cytoplasm.
Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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