Thermo Fisher Scientific DRG1 Polyclonal Antibody
Rabbit에서 유래한 DRG1 폴리클로날 항체로 Western blot 및 Immunoprecipitation에 적합합니다. 인간 DRG1의 200-250번 잔기 영역을 면역원으로 사용하였으며, 1 mg/mL 농도의 액상 형태로 제공됩니다. 4°C 보관, 습식 얼음 배송.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
Immunoprecipitation (IP)
- Tested Dilution: 2–10 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 200 to 250 of human Developmentally-regulated GTP-binding protein 1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage conditions | 4°C |
| Shipping conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Bovine
Target Information
Catalyzes the conversion of GTP to GDP through hydrolysis of the gamma-phosphate bond in GTP (PubMed:29915238, PubMed:23711155).
Appears to have an intrinsic GTPase activity that is stimulated by ZC3H15/DFRP1 binding, likely by increasing the affinity for potassium ions (PubMed:23711155).
When hydroxylated at C-3 of Lys-22 by JMJD7, may bind to RNA and play a role in translation (PubMed:19819225, PubMed:29915238).
Binds to microtubules and promotes microtubule polymerization and stability required for mitotic spindle assembly during prophase to anaphase transition.
GTPase activity is not necessary for these microtubule-related functions (PubMed:28855639).
[UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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