Thermo Fisher Scientific TrkC Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1:500–1:3,000

Product Specifications

Product Specific Information

• Recommended positive controls: 293T, A431, H1299, HeLaS3, Molt-4, Raji, NIH-3T3
• Predicted reactivity: Mouse (91%), Rat (91%), Pig (96%), Chicken (81%), Rhesus Monkey (100%), Chimpanzee (99%), Bovine (92%)
• Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Target Information

NTRK3 (TRKC) belongs to the neurotrophic factor family of related polypeptides central to the development and maintenance of the mammalian nervous system. Known substrates for the TRK receptors are SHC, PI-3 kinase, and PLCG1. The different isoforms do not have identical signaling properties. The protein is widely expressed, mainly in nervous tissue. Isoform B is expressed more in the adult brain compared to the fetal brain. TRKC is subject to ligand-mediated auto-phosphorylation. The protein structure contains two immunoglobulin-like C2-type domains and two leucine-rich (LRR) repeats.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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