Thermo Fisher Scientific PFKP Monoclonal Antibody (OTI1F2)
PFKP 단백질을 인식하는 Thermo Fisher Scientific의 단클론 항체로, Western blot, IHC, ICC, Flow cytometry 등 다양한 응용에 사용 가능. Human 반응성, Mouse IgG1 형식이며, 액상 형태로 제공. 연구용으로만 사용 가능.
- 판매단위
- pk
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:2,000 | - |
| Immunohistochemistry (IHC) | - | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 | - |
| Immunocytochemistry (ICC/IF) | 1:100 | - |
| Flow Cytometry (Flow) | 1:100 | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1F2 |
| Immunogen | Full length human recombinant protein of PFKP produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.56 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2724999 |
Target Information
Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the γ-phosphate of ATP, onto an acceptor amino acid in a substrate protein. Through this mechanism, protein kinases mediate most signal transduction in eukaryotic cells, regulating metabolism, transcription, cell cycle progression, cytoskeletal rearrangement, cell movement, apoptosis, and differentiation.
With more than 500 gene products, the protein kinase family is one of the largest in eukaryotes. They are classified into 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The AGC kinase group consists of 63 kinases, including:
- Cyclic nucleotide-regulated protein kinase (PKA & PKG) family
- Diacylglycerol-activated/phospholipid-dependent protein kinase C (PKC) family
- RAC/Akt protein kinase family
- Kinases that phosphorylate G protein-coupled receptors (ARK family)
- Kinases that phosphorylate ribosomal protein S6 (RSK family)
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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