Thermo Fisher Scientific SAP30L Polyclonal Antibody
Thermo Fisher Scientific의 SAP30L 폴리클로날 항체는 Rat 종에 반응하며 Western Blot과 Peptide ELISA에 적합합니다. Goat IgG 기반으로 제작되었으며, 고순도 액상 형태로 제공되어 안정적인 단백질 검출에 활용됩니다. 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 0.3–1 µg/mL
Publications
- [References not provided]
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Rat |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide with sequence C-RLDQKSEGSKQLE (aa 170–182) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2933316 |
Product Specific Information
This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:32,000.
Target Information
A novel TGF-beta up-regulated mRNA species, the Sin3-associated protein 30-like (SAP30L), has been identified. The predicted nuclear localization signal of SAP30L is sufficient for nuclear transport of the protein, although mutating it does not completely remove SAP30L from the nuclei. Due to its nuclear localization and close homology to SAP30, it is thought that SAP30L might play a role in recruiting the Sin3-histone deacetylase complex to specific co-repressor complexes in response to TGF-beta, leading to silencing of proliferation-driving genes in differentiating intestinal epithelial cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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