ELK Biotechnology UBF-1 rabbit pAb
UBF-1 rabbit pAb는 인간, 마우스, 랫트 시료에서 사용 가능한 폴리클로날 항체로, 핵과 인(nucleolus)에서 발현되는 UBF 단백질을 검출합니다. WB, IHC, IF, ELISA에 적합하며, 고순도의 IgG로 제작되어 안정적인 결과를 제공합니다.
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제품명
UBF-1 rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Alternative Names | UBTF; UBF; UBF1; Nucleolar transcription factor 1; Autoantigen NOR-90; Upstream-binding factor 1; UBF-1 |
| Applications | WB; IHC; IF; ELISA |
| Recommended Dilutions | Western Blot: 1/500 - 1/2000 Immunohistochemistry: 1/100 - 1/300 ELISA: 1/20000 Not yet tested in other applications |
| Immunogen | The antiserum was produced against synthesized peptide derived from human UBF1. AA range: 501–550 |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 90 kD |
| Gene ID (Human) | 7343 |
| Human Swiss-Prot No | P17480 |
| Cellular Localization | Nucleus, nucleolus |
| Species Reactivity | Human; Mouse; Rat |
제품 설명 (Background)
This gene encodes a member of the HMG-box DNA-binding protein family. The encoded protein plays a critical role in ribosomal RNA transcription as a key component of the pre-initiation complex, mediating the recruitment of RNA polymerase I to rDNA promoter regions. The encoded protein may also play important roles in chromatin remodeling and pre-rRNA processing, and its activity is regulated by both phosphorylation and acetylation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Pseudogenes of this gene are located on the short arm of chromosomes 3, 11 and X and the long arm of chromosome 11. [provided by RefSeq, Aug 2011]
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