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ELK Biotechnology TYR rabbit pAb
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ELK Biotechnology TYR rabbit pAb

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Tyrosinase 단백질을 인식하는 토끼 폴리클로날 항체로, Western Blot 및 ELISA에 적합합니다. 인간 유래 합성 펩타이드를 면역원으로 사용하였으며, 멜라노솜 막 단백질 검출에 활용됩니다. -20°C에서 1년 보관 가능합니다.

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ELK Biotechnology ES3659-100UL TYR rabbit pAb, 100UL pk판매 단위 pk ·
재고 확인 필요
402,000원VAT 포함 442,200원
ELK Biotechnology ES3659-50UL TYR rabbit pAb, 50UL pk판매 단위 pk ·
재고 확인 필요
301,000원VAT 포함 331,100원

ELK Biotechnology · ELK Biotechnology TYR rabbit pAb

ELK Biotechnology TYR rabbit pAb

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항목 내용
Product Name TYR rabbit pAb
Alternative Names TYR; Tyrosinase; LB24-AB; Monophenol monooxygenase; SK29-AB; Tumor rejection antigen AB
Applications WB; ELISA
Recommended Dilutions Western Blot: 1/500 - 1/2000
ELISA: 1/10000
Not yet tested in other applications.
Immunogen The antiserum was produced against synthesized peptide derived from human Tyrosinase (AA range: 471–520).
Host Rabbit
Storage -20°C / 1 year
Clonality Polyclonal
Isotype IgG
Concentration 1 mg/ml
Observed Band 80 kD
Gene ID (Human) 7299
Human Swiss-Prot No. P14679
Species Reactivity Human; Monkey
Cellular Localization Melanosome membrane; Single-pass type I membrane protein. Proper trafficking to melanosome is regulated by SGSM2, ANKRD27, RAB9A, RAB32, and RAB38.

Background

Tyrosinase (TYR) is an enzyme that catalyzes the first two steps, and at least one subsequent step, in the conversion of tyrosine to melanin. It possesses both tyrosine hydroxylase and dopa oxidase catalytic activities and requires copper for its function. Mutations in this gene cause oculocutaneous albinism, while nonpathologic polymorphisms contribute to skin pigmentation variation. The human genome also contains a pseudogene similar to the 3′ half of this gene.
[provided by RefSeq, Oct 2008]

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