ELK Biotechnology TIS11B rabbit pAb
TIS11B 단백질을 인식하는 토끼 폴리클로날 항체로, WB, IHC, IF, ELISA에 사용 가능. 인간, 생쥐, 랫트 시료에 반응하며, 세포 내 핵과 세포질에 존재하는 TIS11B 단백질 검출에 적합. 고순도 IgG 형태로 제공.
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ELK Biotechnology TIS11B rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | TIS11B rabbit pAb |
| Alternative Names | ZFP36L1; BERG36; BRF1; ERF1; RNF162B; TIS11B; Zinc finger protein 36; C3H1 type-like 1; Butyrate response factor 1; EGF-response factor 1; ERF-1; Protein TIS11B |
| Applications | WB; IHC; IF; ELISA |
| Recommended Dilutions | Western Blot: 1/500–1/2000 Immunohistochemistry: 1/100–1/300 ELISA: 1/10000 Not yet tested in other applications |
| Immunogen | The antiserum was produced against synthesized peptide derived from human TIS11B (AA range: 58–107) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 36 kDa |
| Gene ID (Human) | 677 |
| Human Swiss-Prot No | Q07352 |
| Cellular Localization | Nucleus, Cytoplasm, Cytoplasmic granule, Cytoplasm (P-body). Shuttles between nucleus and cytoplasm in an XPO1/CRM1-dependent manner. Component of cytoplasmic stress granules and localizes in processing bodies (PBs). |
| Species Reactivity | Human; Mouse; Rat |
Background
This gene is a member of the TIS11 family of early response genes, which are induced by various agonists such as the phorbol ester TPA and the polypeptide mitogen EGF. This gene is well conserved across species and has a promoter that contains motifs seen in other early-response genes. The encoded protein contains a distinguishing putative zinc finger domain with a repeating cys-his motif. This putative nuclear transcription factor most likely functions in regulating the response to growth factors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. (provided by RefSeq, Sep 2011)
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