ELK Biotechnology SR-3A rabbit pAb
인간, 쥐, 생쥐에서 반응하는 SR-3A rabbit polyclonal antibody. WB, IHC, IF, ELISA 적용 가능. 인간 5-HT-3A 펩타이드(AA 161-210)로 면역 생성. 세포막 및 시냅스에 위치한 serotonin-gated ion channel 수용체 검출에 적합.
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ELK Biotechnology SR-3A rabbit pAb
제품 개요
SR-3A rabbit polyclonal antibody는 인간 5-HT-3A 수용체를 인식하는 항체로, 세로토닌 수용체 연구에 적합합니다. WB, IHC, IF, ELISA 등 다양한 응용 분야에서 사용 가능합니다.
제품 사양
| 항목 | 내용 |
|---|---|
| Product name | SR-3A rabbit pAb |
| Alternative Names | HTR3A; 5HT3R; HTR3; 5-hydroxytryptamine receptor 3A; 5-HT3-A; 5-HT3A; 5-hydroxytryptamine receptor 3; 5-HT-3; 5-HT3R; Serotonin receptor 3A; Serotonin-gated ion channel receptor |
| Applications | WB; IHC; IF; ELISA |
| Recommended Dilutions | WB: 1/500–1/2000; IHC: 1/100–1/300; IF: 1/200–1/1000; ELISA: 1/10000; Other applications not yet tested |
| Immunogen | Synthesized peptide derived from human 5-HT-3A (AA range: 161–210) |
| Host Species | Rabbit |
| Storage | -20°C, 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 55 kD |
| GeneID (Human) | 3359 |
| Human Swiss-Prot No | P46098 |
| Cellular Localization | Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. |
| Species Reactivity | Human; Rat; Mouse |
Background
The product of this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit A of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. The heteromeric combination of A and B subunits is necessary for full functional features, as either subunit alone results in receptors with low conductance and response amplitude. Alternatively spliced transcript variants encoding different isoforms have been identified. (RefSeq, Jul 2008)
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