ELK Biotechnology Ribosomal Protein S6 rabbit pAb
Ribosomal Protein S6 rabbit pAb는 인간, 마우스, 랫트에서 반응하는 다클론 항체로, WB, IHC, IF, ELISA에 적합합니다. 단백질 합성 관련 S6 단백질을 인식하며, 세포 성장 및 증식 연구에 활용됩니다. -20°C에서 1년 보관 가능합니다.
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Ribosomal Protein S6 rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | Ribosomal Protein S6 rabbit pAb |
| Alternative Names | RPS6; OK/SW-cl.2; 40S ribosomal protein S6; Phosphoprotein NP33 |
| Applications | WB; IHC; IF; ELISA |
| Recommended Dilutions | WB: 1/500–1/2000 IHC: 1/100–1/300 IF: 1/200–1/1000 ELISA: 1/5000 Other applications not yet tested |
| Immunogen | Synthesized peptide derived from human S6 Ribosomal Protein (AA 191–240) |
| Host | Rabbit |
| Storage | -20°C, 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 28 kDa |
| Gene ID (Human) | 6194 |
| Human Swiss-Prot No. | P62753 |
| Cellular Localization | Nucleus, nucleoplasm, nucleolus, cytoplasm, cytosol, ribosome, polysome, small ribosomal subunit, membrane, cytosolic small ribosomal subunit, dendrite, intracellular ribonucleoprotein complex, cytoplasmic ribonucleoprotein granule |
| Species Reactivity | Human, Mouse, Rat |
Background
Ribosomes are organelles that catalyze protein synthesis and consist of a small 40S subunit and a large 60S subunit, composed of four RNA species and about 80 distinct proteins. This gene encodes a cytoplasmic ribosomal protein that is part of the 40S subunit and belongs to the S6E family. It is the major substrate of ribosomal protein kinases, with phosphorylation occurring on five C-terminal serine residues. Phosphorylation is induced by growth factors, tumor-promoting agents, and mitogens, while dephosphorylation occurs at growth arrest. The protein may regulate cell growth and proliferation by selectively translating specific mRNA classes. As typical for ribosomal protein genes, multiple processed pseudogenes exist.
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