ELK Biotechnology RGS10 rabbit pAb

제품명

RGS10 rabbit pAb

제품 개요

RGS10 단백질은 G 단백질 신호 조절(RGS) 패밀리에 속하며, Gα 서브유닛의 GTPase 활성화를 촉진하여 신호를 음성 조절하는 역할을 합니다. 본 항체는 인간 RGS10 합성 펩타이드(AA 80-129)를 면역원으로 제작된 토끼 폴리클로날 항체입니다.

제품 정보

Background

Regulator of G protein signaling (RGS) family members are regulatory molecules that act as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins. RGS proteins deactivate G protein subunits of the Gi alpha, Go alpha, and Gq alpha subtypes, driving them into their inactive GDP-bound forms. RGS10 specifically associates with activated Gαi3 and Gαz subunits and is localized in the nucleus. Two transcript variants encoding different isoforms have been identified for this gene (RefSeq, Jul 2008).