ELK Biotechnology RARβ rabbit pAb
RARβ rabbit pAb는 인간 Retinoic Acid Receptor Beta를 인식하는 다클론 항체로, WB, IHC, IF, ELISA에 사용 가능합니다. 핵 및 세포질에서 발현되는 단백질을 검출하며, 세포 성장 및 분화 연구에 적합합니다. -20°C에서 1년 보관 가능합니다.
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제품명
RARβ rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Alternative Names | RARB; HAP; NR1B2; Retinoic acid receptor beta; RAR-beta; HBV-activated protein; Nuclear receptor subfamily 1 group B member 2; RAR-epsilon |
| Applications | WB; IHC; IF; ELISA |
| Recommended Dilutions | Western Blot: 1/500 - 1/2000 Immunohistochemistry: 1/100 - 1/300 ELISA: 1/20000 Not yet tested in other applications. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human Retinoic Acid Receptor beta. AA range: 331-380 |
| Host Species | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 50 kD |
| Gene ID (Human) | 5915 |
| Human Swiss-Prot No. | P10826 |
| Cellular Localization | Nucleus, Cytoplasm. Isoform Beta-1: Nucleus Isoform Beta-2: Nucleus Isoform Beta-4: Cytoplasm |
| Species Reactivity | Human, Mouse |
Background
This gene encodes retinoic acid receptor beta, a member of the thyroid-steroid hormone receptor superfamily of nuclear transcriptional regulators. This receptor localizes to the cytoplasm and to subnuclear compartments. It binds retinoic acid, the biologically active form of vitamin A which mediates cellular signalling in embryonic morphogenesis, cell growth and differentiation. It is thought that this protein limits growth of many cell types by regulating gene expression. The gene was first identified in a hepatocellular carcinoma where it flanks a hepatitis B virus integration site. Alternate promoter usage and differential splicing result in multiple transcript variants. (provided by RefSeq, Mar 2014)
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