ELK Biotechnology Rad23B rabbit pAb
Rad23B 단백질을 인식하는 토끼 폴리클로날 항체로, WB, IHC, IF, ELISA에 적합합니다. 인간 RAD23B 유래 펩타이드로 면역화되었으며, 핵과 세포질에서 발현되는 단백질 검출에 유용합니다. -20°C에서 1년 보관 가능합니다.
- 판매단위
- pk
카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다ELK Biotechnology · ELK Biotechnology Rad23B rabbit pAb
제품명
Rad23B rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Alternative Names | RAD23B; UV excision repair protein RAD23 homolog B; HR23B; hHR23B; XP-C repair-complementing complex 58 kDa protein; p58 |
| Applications | WB; IHC; IF; ELISA |
| Recommended Dilutions | Western Blot: 1/500 - 1/2000 Immunohistochemistry: 1/100 - 1/300 Immunofluorescence: 1/200 - 1/1000 ELISA: 1/20000 Not yet tested in other applications. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human RAD23B (AA range: 1–50). |
| Host | Rabbit |
| Storage | -20°C, 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 58 kDa |
| Gene ID (Human) | 5887 |
| Human Swiss-Prot No. | P54727 |
| Species Reactivity | Human; Mouse; Rat |
| Cellular Localization | Nucleus, Cytoplasm. The intracellular distribution is cell cycle dependent. Localized to the nucleus and cytoplasm during G1 phase. Nuclear levels decrease during S-phase; upon entering mitosis, relocalizes in the cytoplasm without association with chromatin. |
Background
The protein encoded by this gene is one of two human homologs of Saccharomyces cerevisiae Rad23, a protein involved in nucleotide excision repair (NER). It is a component of the protein complex that complements the NER defect of xeroderma pigmentosum group C (XP-C) cell extracts in vitro.
This protein interacts with and enhances the nucleotide excision activity of 3-methyladenine-DNA glycosylase (MPG), suggesting a role in DNA damage recognition in base excision repair.
It contains an N-terminal ubiquitin-like domain that interacts with the 26S proteasome, indicating involvement in the ubiquitin-mediated proteolytic pathway.
Alternative splicing results in multiple transcript variants encoding distinct isoforms.
(Provided by RefSeq, Sep 2011)
ELK Biotechnology 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.