
ELK Biotechnology PSMD11 rabbit pAb
PSMD11 단백질을 인식하는 토끼 폴리클로날 항체로, WB, IHC, IF, ELISA에 적합합니다. 인간 유래 합성 펩타이드로 면역화되었으며, 42kDa 밴드 검출에 사용됩니다. 핵과 세포질에 발현되는 PSMD11 단백질 연구에 유용합니다.
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PSMD11 rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | PSMD11 rabbit pAb |
| Alternative Names | PSMD11; 26S proteasome non-ATPase regulatory subunit 11; 26S proteasome regulatory subunit RPN6; 26S proteasome regulatory subunit S9; 26S proteasome regulatory subunit p44.5 |
| Applications | WB; IHC; IF; ELISA |
| Recommended Dilutions | Western Blot: 1/500 - 1/2000 Immunohistochemistry: 1/100 - 1/300 ELISA: 1/10000 Not yet tested in other applications |
| Immunogen | The antiserum was produced against synthesized peptide derived from human PSMD11 (AA range: 271–320) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 42 kDa |
| GeneID (Human) | 5717 |
| Human Swiss-Prot No | O00231 |
| Cellular Localization | Nucleus; Cytoplasm, cytosol |
| Species Reactivity | Human; Mouse |
Background
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of two complexes: a 20S core and a 19S regulator.
The 20S core consists of four rings of 28 non-identical subunits — two rings of seven alpha subunits and two rings of seven beta subunits.
The 19S regulator includes a base containing six ATPase subunits and two non-ATPase subunits, and a lid containing up to ten non-ATPase subunits.
Proteasomes are distributed throughout eukaryotic cells at high concentrations and cleave peptides in an ATP/ubiquitin-dependent, non-lysosomal process.
This gene encodes a member of the proteasome subunit S9 family functioning as a non-ATPase subunit of the 19S regulator and is phosphorylated by AMP-activated protein kinase.
Alternatively spliced transcript variants have been observed for this gene. (Provided by RefSeq)
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