ELK Biotechnology PSCA rabbit pAb
PSCA 단백질을 인식하는 토끼 폴리클로날 항체로, WB, ELISA, IHC에 사용 가능. 인간 및 생쥐 시료에 반응하며, 세포막 GPI-앵커 단백질 검출에 적합. -20°C에서 1년 보관 가능.
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ELK Biotechnology PSCA rabbit pAb
제품 개요
PSCA (Prostate Stem Cell Antigen)을 인식하는 토끼 폴리클로날 항체로, 전립선 및 다양한 조직에서 발현되는 세포막 단백질 검출에 사용됩니다.
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | PSCA rabbit pAb |
| Alternative Names | PSCA; Prostate stem cell antigen |
| Applications | WB; ELISA; IHC |
| Recommended Dilutions | WB 1:500–2000; IHC-p 1:50–300; ELISA 1:2000–20000 |
| Immunogen | Synthesized peptide derived from human Prostate Stem Cell Antigen (AA range: 41–90) |
| Species Reactivity | Human; Mouse |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 29 kDa |
| GeneID (Human) | 8000 |
| Human Swiss-Prot No | O43653 |
| Cellular Localization | Cell membrane; Lipid-anchor, GPI-anchor |
| Storage | -20°C / 1 year |
| Host | Rabbit |
Background
This gene encodes a glycosylphosphatidylinositol (GPI)-anchored cell membrane glycoprotein. In addition to being highly expressed in the prostate, it is also expressed in the bladder, placenta, colon, kidney, and stomach. This gene is up-regulated in a large proportion of prostate cancers and is also detected in cancers of the bladder and pancreas. A polymorphism resulting in an upstream start codon in some individuals is thought to be associated with a risk for certain gastric and bladder cancers. Alternative splicing results in multiple transcript variants.
[Provided by RefSeq, Feb 2010]
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