ELK Biotechnology PR rabbit pAb
Progesterone receptor(PR)를 인식하는 rabbit polyclonal antibody로, WB·IHC·IF·ELISA에 사용 가능. 인간 유래 합성 펩타이드(AA 371-420)를 면역원으로 제작. 핵 및 세포질 위치 검출에 적합하며 Human, Rat, Mouse 반응성 보유.
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제품명
PR rabbit pAb
공급업체
ELK Biotechnology
제품 개요
Progesterone receptor(PR)에 대한 rabbit polyclonal antibody로, 생식 관련 연구 및 호르몬 반응성 단백질 검출에 적합합니다.
제품 정보
| 항목 | 내용 |
|---|---|
| Alternative Names | PGR; NR3C3; Progesterone receptor; PR; Nuclear receptor subfamily 3 group C member 3 |
| Applications | WB; IHC; IF; ELISA |
| Recommended Dilutions | Western Blot: 1/500–1/2000 Immunohistochemistry: 1/100–1/300 Immunofluorescence: 1/200–1/1000 ELISA: 1/5000 Not yet tested in other applications |
| Immunogen | Synthesized peptide derived from human Progesterone Receptor (AA range: 371–420) |
| Host | Rabbit |
| Storage | -20 °C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 99 kD |
| GeneID (Human) | 5241 |
| Human Swiss-Prot No | P06401 |
| Cellular Localization | Nucleus; Cytoplasm; Nucleoplasmic shuttling is hormone- and cell cycle-dependent. On hormone stimulation, retained in cytoplasm in G(1) and G(2)/M phases. Isoform A: Mainly nuclear. Isoform 4: Mitochondrion outer membrane |
| Species Reactivity | Human; Rat; Mouse |
Background
This gene encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy. This gene uses two distinct promoters and translation start sites in the first exon to produce several transcript variants, both protein-coding and non-protein-coding. Isoforms A and B are identical except for an additional 165 amino acids found in the N-terminus of isoform B and mediate their own response genes and physiologic effects with little overlap. (provided by RefSeq, Sep 2015)
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