ELK Biotechnology PPP2R3C rabbit pAb
PPP2R3C 단백질을 인식하는 토끼 다클론 항체로, WB, ELISA, IHC에 적합합니다. 인간 유래 합성 펩타이드로 면역하여 제작되었으며, 핵과 세포질에 위치한 단백질 검출에 유용합니다. 장기 보관은 -20°C에서 가능합니다.
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제품명
PPP2R3C rabbit pAb
제품 개요
PPP2R3C 단백질에 특이적인 토끼 다클론 항체입니다. 세포 주기 단계에 따라 핵과 세포질에 위치하는 단백질을 검출하는 데 사용됩니다.
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | PPP2R3C rabbit pAb |
| Alternative Names | PPP2R3C; C14orf10; G5PR; Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma; Protein phosphatase subunit G5PR; Rhabdomyosarcoma antigen MU-RMS-40.6A/6C |
| Applications | WB; ELISA; IHC |
| Recommended Dilutions | WB 1:500–2000; IHC-p 1:50–300; ELISA 1:2000–20000 |
| Immunogen | The antiserum was produced against synthesized peptide derived from human PPP2R3C (AA range: 165–214) |
| Host | Rabbit |
| Storage | -20°C, 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 55 kD |
| Gene ID (Human) | 55012 |
| Human Swiss-Prot No | Q969Q6 |
| Cellular Localization | Nucleus and cytoplasm; excluded from nucleoli. Localization is cell cycle-dependent and shifts to the cytoplasm during cytokinesis. |
| Species Reactivity | Human; Mouse; Rat |
Background
This gene encodes a regulatory subunit of the serine/threonine phosphatase, protein phosphatase 2. The protein localizes to both nuclear and cytoplasmic regions depending on the cell cycle phase. Homozygous conditional knockout mice for this gene exhibit reduced numbers and impaired proliferation of immune system B cells. This protein may regulate the expression of the P-glycoprotein ATP-binding cassette transporter through its phosphatase activity. Alternative splicing results in multiple transcript variants.
[Provided by RefSeq, Feb 2015]
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