Thermo Fisher Scientific PSMC4 Polyclonal Antibody
Thermo Fisher Scientific의 PSMC4 Polyclonal Antibody는 인간, 마우스, 랫트에서 반응하는 고품질 Rabbit IgG 항체입니다. Western blot, IHC, ICC/IF 등에 사용 가능하며, 항원 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용됩니다.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 | - |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human PSMC4. Recombinant protein control fragment (Product #RP-102166). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2646064 |
Product Specific Information
Immunogen sequence:
LEDLYSRYKK LQQELEFLEV QEEYIKDEQK NLKKEFLHAQ EEVKRIQSIP LVIGQFLEAV DQNTAIVGST TGSNYYVRIL STIDRELLKP NASVALHKHS NA
Highest antigen sequence identity to the following orthologs:
- Mouse: 100%
- Rat: 100%
Target Information
The 26S proteasome is a multicatalytic proteinase complex composed of a 20S core and a 19S regulator. The 20S core consists of four rings of 28 non-identical subunits (two alpha and two beta rings). The 19S regulator includes a base with ATPase and non-ATPase subunits and a lid with up to 10 non-ATPase subunits. Proteasomes are widely distributed in eukaryotic cells and cleave peptides in an ATP/ubiquitin-dependent, non-lysosomal pathway. The immunoproteasome plays a key role in processing class I MHC peptides.
This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases with chaperone-like activity. It interacts with a nuclear hormone receptor superfamily member expressed in liver and with gankyrin, a liver oncoprotein. Two transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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