ELK Biotechnology PKR1 rabbit pAb
PKR1 단백질을 인식하는 토끼 폴리클로날 항체로, WB, IF, ELISA, IHC에 사용 가능. 사람, 생쥐, 랫트에 반응하며 세포막 단백질 검출에 적합. -20°C에서 1년 보관 가능하며, 1 mg/ml 농도로 제공.
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제품명
PKR1 rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Alternative Names | PROKR1; GPR73; PKR1; Prokineticin receptor 1; PK-R1; G-protein coupled receptor 73; G-protein coupled receptor ZAQ; GPR73a |
| Applications | WB; IF; ELISA; IHC |
| Recommended Dilutions | WB 1:500–2000; IF/ICC 1:100–500; ELISA 1:5000–20000; IHC-p 1:100–500 |
| Immunogen | The antiserum was produced against synthesized peptide derived from human PKR1 (AA range: 19–68). |
| Host | Rabbit |
| Storage | -20°C, 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 45 kD |
| Gene ID (Human) | 10887 |
| Human Swiss-Prot No. | Q8TCW9 |
| Cellular Localization | Cell membrane; Multi-pass membrane protein |
| Species Reactivity | Human; Mouse; Rat |
Background
Prokineticin receptor 1 (PROKR1) is a member of the G-protein-coupled receptor family. This protein binds to prokineticins (1 and 2), leading to activation of MAPK and STAT signaling pathways. Prokineticins are protein ligands involved in angiogenesis and inflammation. The encoded protein is expressed in peripheral tissues including the circulatory, respiratory, reproductive, endocrine, and gastrointestinal systems. It may play a role in signaling during primordial follicle formation in the human fetal ovary. Sequence variants in this gene may be associated with recurrent miscarriage.
[Provided by RefSeq, Aug 2016]
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