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ELK Biotechnology PIAS 1 rabbit pAb
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PIAS1 단백질에 특이적인 토끼 다클론 항체로, WB, IHC, IF, ELISA에 사용 가능. 인간 및 생쥐 시료에 반응하며, 핵 내 speckle과 PML body에서 발현. 합성 펩타이드(AA 10-59)로 면역화하여 제작됨.
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ELK Biotechnology ES3203-100UL PIAS 1 rabbit pAb, 100UL pk판매 단위 pk ·
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402,000원VAT 포함 442,200원
ELK Biotechnology ES3203-50UL PIAS 1 rabbit pAb, 50UL pk판매 단위 pk ·
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301,000원VAT 포함 331,100원
ELK Biotechnology · ELK Biotechnology PIAS 1 rabbit pAb
제품명
PIAS 1 rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Alternative Names | PIAS1; DDXBP1; E3 SUMO-protein ligase PIAS1; DEAD/H box-binding protein 1; Gu-binding protein; GBP; Protein inhibitor of activated STAT protein 1; RNA helicase II-binding protein |
| Applications | WB; IHC; IF; ELISA |
| Recommended Dilutions | Western Blot: 1/500 - 1/2000 Immunohistochemistry: 1/100 - 1/300 ELISA: 1/10000 Not yet tested in other applications |
| Immunogen | The antiserum was produced against synthesized peptide derived from human PIAS1 (AA range: 10–59) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 72 kDa |
| Gene ID (Human) | 8554 |
| Human Swiss-Prot No. | O75925 |
| Cellular Localization | Nucleus speckle; Nucleus, PML body. Interaction with CSRP2 may induce partial redistribution along the cytoskeleton. |
| Species Reactivity | Human; Mouse |
Background
This gene encodes a member of the protein inhibitor of activated STAT (PIAS) family. PIAS proteins function as SUMO E3 ligases and play important roles in many cellular processes by mediating the sumoylation of target proteins.
This protein acts as a transcriptional coregulator in multiple pathways, including STAT1 and NF-κB signaling. Alternate splicing results in multiple transcript variants.
[Provided by RefSeq, Mar 2016]
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