ELK Biotechnology PDHA1 rabbit pAb
PDHA1 단백질을 인식하는 토끼 폴리클로날 항체로, WB, IHC, IF, ELISA에 사용 가능. 인간, 마우스, 랫트 반응성. 미토콘드리아 매트릭스 내 PDH 복합체 연구에 적합. -20°C에서 1년 보관 가능.
- 판매단위
- pk
카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다ELK Biotechnology · ELK Biotechnology PDHA1 rabbit pAb
PDHA1 rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | PDHA1 rabbit pAb |
| Alternative Names | PDHA1; PHE1A; Pyruvate dehydrogenase E1 component subunit alpha; somatic form, mitochondrial; PDHE1-A type I |
| Applications | WB; IHC; IF; ELISA |
| Recommended Dilutions | WB: 1/500–1/2000 IHC: 1/100–1/300 ELISA: 1/40000 Other applications not yet tested |
| Immunogen | Synthesized peptide derived from human PDHA1 (AA range: 314–363) |
| Host | Rabbit |
| Storage | -20°C, 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 43 kDa |
| Gene ID (Human) | 5160 |
| Human Swiss-Prot No | P08559 |
| Cellular Localization | Mitochondrion matrix |
| Species Reactivity | Human; Mouse; Rat |
Background
The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO₂, providing the primary link between glycolysis and the tricarboxylic acid (TCA) cycle.
The PDH complex consists of multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2), and lipoamide dehydrogenase (E3).
The E1 enzyme is a heterotetramer of two alpha and two beta subunits. This gene encodes the E1 alpha 1 subunit containing the E1 active site, playing a key role in PDH complex function.
Mutations in this gene are associated with pyruvate dehydrogenase E1-alpha deficiency and X-linked Leigh syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified (RefSeq, Mar 2010).
ELK Biotechnology 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.