ELK Biotechnology Pax-5 rabbit pAb
Pax-5 rabbit pAb는 인간 및 마우스에 반응하는 다클론 항체로, B세포 특이 전사인자 Pax-5 검출에 적합합니다. Western blot과 ELISA에 사용 가능하며, 고순도의 IgG 형태로 -20°C에서 1년 보관 가능합니다. 세포핵에 위치한 Pax-5 단백질 연구에 유용합니다.
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Pax-5 rabbit pAb
공급업체: ELK Biotechnology
제품 개요
Pax-5 rabbit pAb는 인간 Pax-5 단백질을 인식하는 다클론성 항체로, B세포 특이 전사인자 연구에 활용됩니다. Western blot 및 ELISA 분석에 적합하며, 인간 및 마우스 시료에서 반응합니다.
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | Pax-5 rabbit pAb |
| Alternative Names | PAX5; Paired box protein Pax-5; B-cell-specific transcription factor; BSAP |
| Applications | WB; ELISA |
| Recommended Dilutions | Western Blot: 1/500 - 1/2000 ELISA: 1/40000 Not yet tested in other applications |
| Immunogen | Synthesized peptide derived from human Pax-5 (AA range: 1–50) |
| Storage | -20°C / 1 year |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 40 kD |
| GeneID (Human) | 5079 |
| Human Swiss-Prot No | Q02548 |
| Cellular Localization | Nucleus |
| Species Reactivity | Human; Mouse |
Background
This gene encodes a member of the paired box (PAX) family of transcription factors. The central feature of this gene family is a novel, highly conserved DNA-binding motif known as the paired box. Paired box transcription factors are important regulators in early development, and alterations in the expression of their genes are thought to contribute to neoplastic transformation.
This gene encodes the B-cell lineage specific activator protein that is expressed at early, but not late stages of B-cell differentiation. Its expression has also been detected in developing CNS and testis, suggesting roles in neural development and spermatogenesis. The gene is located at 9p13, involved in t(9;14)(p13;q32) translocations recurring in small lymphocytic lymphomas of the plasmacytoid subtype and in derived large-cell lymphomas.
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