ELK Biotechnology PAF65α rabbit pAb
PAF65α 단백질을 인식하는 토끼 폴리클로날 항체로, WB, IHC, IF, ELISA에 사용 가능. 인간 TAF6L 유래 펩타이드로 면역화됨. 핵 내 단백질 검출에 적합하며, -20°C에서 1년 보관 가능.
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ELK Biotechnology PAF65α rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | PAF65α rabbit pAb |
| Alternative Names | TAF6L; PAF65A; TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L; PCAF-associated factor 65-alpha; PAF65-alpha |
| Applications | WB; IHC; IF; ELISA |
| Recommended Dilutions | Western Blot: 1/500 - 1/2000 Immunohistochemistry: 1/100 - 1/300 ELISA: 1/40000 Not yet tested in other applications |
| Immunogen | The antiserum was produced against synthesized peptide derived from human TAF6L (AA range: 31–80) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 68 kDa |
| GeneID (Human) | 10629 |
| Human Swiss-Prot No | Q9Y6J9 |
| Cellular Localization | Nucleus |
| Species Reactivity | Human; Mouse |
Background
Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals.
TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors (TAFs).
TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition, or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation.
This gene encodes a protein that is a component of the PCAF histone acetylase complex and is structurally similar to one of the histone-like TAFs.
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