CacheBy
ELK Biotechnology p53RFP rabbit pAb
원본

ELK Biotechnology p53RFP rabbit pAb

상품 한눈에 보기

Human 및 Mouse 시료에 반응하는 p53RFP rabbit polyclonal antibody로, Western blot과 ELISA에 적합합니다. 내부 human p53RFP 펩타이드로 면역화되었으며, 35kD 밴드 검출. -20°C에서 1년 보관 가능.

판매단위
pk
카탈로그 보기

카탈로그

2개 옵션
회원가입 없이 바로 구매하세요
가입하지 않아도 비회원가로 구매하실 수 있습니다.
ELK Biotechnology ES3129-100UL p53RFP rabbit pAb, 100UL pk판매 단위 pk ·
재고 확인 필요
402,000원VAT 포함 442,200원
ELK Biotechnology ES3129-50UL p53RFP rabbit pAb, 50UL pk판매 단위 pk ·
재고 확인 필요
301,000원VAT 포함 331,100원

ELK Biotechnology · ELK Biotechnology p53RFP rabbit pAb

ELK Biotechnology p53RFP rabbit pAb

제품 개요

p53RFP rabbit polyclonal antibody는 인간 p53RFP 단백질의 내부 영역에서 유래한 합성 펩타이드로 면역화된 항체입니다. Western blot 및 ELISA 분석에 적합하며, apoptosis 관련 단백질 연구에 활용됩니다.

제품 사양

항목 내용
Product name p53RFP rabbit pAb
Alternative Names RNF144B; IBRDC2; P53RFP; E3 ubiquitin-protein ligase RNF144B; IBR domain-containing protein 2; RING finger protein 144B; p53-inducible RING finger protein
Applications WB; ELISA
Recommended Dilutions Western Blot: 1/500 - 1/2000
ELISA: 1/40000
Other applications not yet tested
Immunogen Synthesized peptide derived from the internal region of human p53RFP
Storage -20°C / 1 year
Host Rabbit
Clonality Polyclonal
Isotype IgG
Concentration 1 mg/ml
Observed Band 35 kD
GeneID (Human) 255488
Human Swiss-Prot No Q7Z419
Cellular Localization Mitochondrion membrane; Single-pass membrane protein; Cytoplasm. Mostly cytosolic, accumulates in submitochondrial domains upon apoptosis induction, synchronized with BAX activation.
Species Reactivity Human; Mouse

Background

  • Caution: Lacks the His residue in the RING-type domain 2, one of the conserved features of the family.
  • Domain: The RING-type zinc finger domain mediates binding to E2 ubiquitin-conjugating enzyme.
  • Function: E3 ubiquitin-protein ligase that transfers ubiquitin from E2 enzymes (UBE2L3, UBE2L6) to substrates such as LCMT2, promoting degradation. Induces apoptosis via TP53/p53-dependent but caspase-independent mechanism.
  • Pathway: Protein modification; protein ubiquitination.
  • PTM: Auto-ubiquitinated.
  • Similarity: Belongs to RBR family, RNF144 subfamily; contains 1 IBR-type zinc finger and 2 RING-type zinc fingers.
  • Subunit: Interacts with UBE2L3, UBE2L6, and LCMT2.
  • Tissue Specificity: Broadly expressed, lowest levels in brain, spleen, and thymus.

ELK Biotechnology 상품 둘러보기

전체보기

문의

0

아직 등록된 문의가 없어요.