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ELK Biotechnology p18 rabbit pAb
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Cyclin-dependent kinase 억제 단백질 p18을 인식하는 rabbit polyclonal antibody. WB, IHC, IF, ELISA에 사용 가능하며, 세포 주기 조절 연구에 적합. 인간, 생쥐, 원숭이에 반응하며, -20°C에서 1년 보관 가능.
- 판매단위
- pk
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ELK Biotechnology ES3099-100UL p18 rabbit pAb, 100UL pk판매 단위 pk ·
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402,000원VAT 포함 442,200원
ELK Biotechnology ES3099-50UL p18 rabbit pAb, 50UL pk판매 단위 pk ·
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301,000원VAT 포함 331,100원
ELK Biotechnology · ELK Biotechnology p18 rabbit pAb
제품명
p18 rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Alternative Names | CDKN2C; CDKN6; Cyclin-dependent kinase 4 inhibitor C; Cyclin-dependent kinase 6 inhibitor; p18-INK4c; p18-INK6 |
| Applications | WB; IHC; IF; ELISA |
| Recommended Dilutions | Western Blot: 1/500 - 1/2000 Immunohistochemistry: 1/100 - 1/300 ELISA: 1/20000 Not yet tested in other applications |
| Immunogen | The antiserum was produced against synthesized peptide derived from human p18 INK. AA range: 111-160 |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 18 kD |
| Gene ID (Human) | 1031 |
| Human Swiss-Prot No | P42773 |
| Cellular Localization | Nucleus, cytoplasm, cytosol |
| Species Reactivity | Human; Mouse; Monkey |
Background
The protein encoded by this gene is a member of the INK4 family of cyclin-dependent kinase inhibitors. It interacts with CDK4 or CDK6 and prevents activation of CDK kinases, functioning as a cell growth regulator controlling cell cycle G1 progression. Ectopic expression suppresses human cell growth in correlation with wild-type RB1 function. Knockout mouse studies suggest roles in regulating spermatogenesis and tumor suppression. Two alternatively spliced transcript variants encoding an identical protein have been reported.
(Provided by RefSeq, Jul 2008)
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