Thermo Fisher Scientific NOTCH1 Monoclonal Antibody (OTI2E7), TrueMAB
인간 NOTCH1 단백질(aa 2280-2556)에 특이적인 Mouse IgG1 단일클론 항체입니다. IHC(P)에서 1:150 희석으로 검증되었습니다. Affinity chromatography로 정제되었으며, PBS/BSA/glycerol buffer에 보관됩니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2E7 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 2280–2556 of human NOTCH1 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The Notch gene family encodes transmembrane proteins containing multiple cysteine-rich EGF-like repeats in the extracellular region. Four Notch genes have been identified in mammals — Notch1, Notch2, Notch3, and Notch4 (Int-3) — which are involved in the differentiation of the nervous system and other tissues. The EGF-like proteins Delta and Serrate act as ligands for Notch1. Mature Notch proteins are heterodimeric receptors composed of an extracellular subunit (NEC) and a transmembrane subunit (Ntm) that includes the intracellular domain.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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