Thermo Fisher Scientific TOE1 Monoclonal Antibody (1D4)
TOE1 단백질을 인식하는 Mouse monoclonal antibody (Clone 1D4). Western blot과 ELISA에 적합하며 인간 시료 반응성. Unconjugated 형태, 액상 제품으로 -20°C에서 보관. 세포 성장 억제 및 snRNA 성숙 관련 연구용에 적합.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
ELISA
- Tested Concentration: 10 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1D4 |
| Immunogen | TOE1 (AAH09364, 1 a.a. ~ 510 a.a) full-length recombinant protein with GST tag (MW of GST tag alone: 26 KDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Storage Buffer | Ascites |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
MAADSDDGAV SAPAASDGGV SKSTTSGEEL VVQVPVVDVQ SNNFKEMWPS LLLAIKTANF VAVDTELSGL GDRKSLLNQC IEERYKAVCH AARTRSILSL GLACFKRQPD KGEHSYLAQV FNLTLLCMEE YVIEPKSVQF LIQHGFNFNQ QYAQGIPYHK GNDKGDESQS QSVRTLFLEL IRARRPLVLH NGLIDLVFLY QNFYAHLPES LGTFTADLCE MFPAGIYDTK YAAEFHARFV ASYLEYAFRK CERENGKQRA AGSPHLTLEF CNYPSSMRDH IDYRCCLPPA THRPHPTSIC DNFSAYGWCP LGPQCPQSHD IDLIIDTDEA AAEDKRRRRR RREKRKRALL NLPGTQTSGE AKDGPPKKQV CGDSIKPEET EQEVAADETR NLPHSKQGNK NDLEMGIKAA RPEIADRATS EVPGSQASPN PVPGDGLHRA GFDAFMTGYV MAYVEVSQGP QPCSSGPWLP ECHNKVYLSG KAVPLTVAKS QFSRSSKAHN QKMKLTWGSS
Target Information
- Inhibits cell growth rate and cell cycle.
- Induces CDKN1A and TGF-beta expression.
- Mediates inhibitory growth effect of EGR1.
- Involved in maturation of snRNAs and snRNA 3'-tail processing (PubMed:28092684).
- [UniProt Reference: Q96GM8-1]
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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