Thermo Fisher Scientific PHLDA2 Polyclonal Antibody

Applications

Immunohistochemistry (Paraffin) (IHC (P))

• Tested Dilution: 3.75 µg/mL

Product Specifications

Product Specific Information

• Tested in Peptide ELISA: antibody detection limit dilution 1:32,000
• Preliminary analysis showed no signal in Western Blot

Target Information

TSSC3 (Tumor-suppressing STF cDNA 3 protein), also known as PHLDA2 (pleckstrin homology-like domain family A member 2), BWR1C, HLDA2 or IPL, is a cytoplasmic protein involved in fetal and placental growth.
It is expressed at high levels in placenta and adult prostate, and at low levels in liver, lung, and brain.
TSSC3 is an apoptosis-related protein acting as a negative growth regulator and is expressed during normal human development.
It is imprinted on placenta, liver, and fetal tissues during embryogenesis and removed once development is complete.
Defects or alterations in the TSSC3 gene are associated with diseases such as lung, ovarian, and breast cancer, rhabdomyosarcoma, Beckwith-Wiedemann syndrome, Wilms tumor, low birth weight, and adrenocortical carcinoma.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

제품 이미지

(이미지 파일명: PA5-142083_PHLDA2_Q53GA4-1_Goat.svg, PA5-142083_PHLDA2_Q53GA4-1_Goat_PDP.jpeg)