Thermo Fisher Scientific ACSL6 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:200-1:500

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human ACSL6. Recombinant protein control fragment (Product #RP-89595). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:ACSL6,uniProtId:Q9UKU0-4,ncbiNodeId:9606,antigenRange:187-297,antigenLength:697,antigenImageFileName:PA5-59191_ACSL6_Q9UKU0-4_Rabbit.svg,antigenImageFileNamePDP:PA5-59191_ACSL6_Q9UKU0-4_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.2 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2637625

Product Specific Information

Immunogen sequence: RYIINTADIS TVIVDKPQKA VLLLEHVERK ETPGLKLIIL MDPFEEALKE RGQKCGVVIK SMQAVEDCGQ ENHQAPVPPQ PDDLSIVCFT SGTTGNPKGA MLTHGNVVAD F

Highest antigen sequence identity to the following orthologs: Mouse - 87%, Rat - 86%.

Target Information

FACL6 is involved in activation of long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. It plays an important role in fatty acid metabolism in brain and the acyl-CoAs produced may be utilized exclusively for the synthesis of the brain lipid. FACL6 is expressed predominantly in erythrocyte precursors, in particular in reticulocytes, fetal blood cells derieved from fetal liver, haemopoietic stem cells from cord blood, bone marrow, and brain. Expression is low at earlier stages of erythroid development but is very high in reticulocytes. This protein is involved in myelodysplastic syndrome (MDS) with basophilia, acute myelogenous leukemia (AML) with eosinophilia, and acute eosinophilic leukemia (AEL). It is characterized by a chromosomal translocation t(5;12)(q31;p13) that involves ETV6 and ACSL6.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.