Thermo Fisher Scientific CXCL10 (IP-10) Monoclonal Antibody (4NY8UN), Alexa Fluor 647, eBioscience
인간 CXCL10(IP-10)을 인식하는 단클론 항체로, Alexa Fluor 647로 표지되어 있습니다. 유세포분석(Flow Cytometry)에 적합하며, 염증 반응 및 T세포 이동 연구에 활용됩니다. 4°C 암소 보관, 동결 금지.
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Applications
Flow Cytometry (Flow)
- Tested Dilution: 5 µL (0.06 µg)/test
- Applications Reported: Intracellular staining followed by flow cytometric analysis
- Applications Tested: Pre-diluted and validated using Intracellular Fixation & Permeabilization Buffer Set (Product # 88-8824-00)
- Recommended protocol: Flow Protocols
- Excitation: 633–647 nm
- Emission: 668 nm
- Laser: Red Laser
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b, kappa |
| Recommended Isotype Control | Mouse IgG2b kappa Isotype Control (eBMG2b), Alexa Fluor™ 647, eBioscience™ |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 4NY8UN |
| Conjugate | Alexa Fluor™ 647 |
| Excitation / Emission Max | 650 / 671 nm |
| Form | Liquid |
| Concentration | 5 µL/test |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 0.2% BSA |
| Contains | 0.09% sodium azide |
| Storage conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2848412 |
Available Formats
Product Specific Information
This 4NY8UN monoclonal antibody reacts with human CXCL10 (Interferon Inducible Protein-10, IP-10), a member of the CXC chemokine family. CXCL10 is secreted by monocytes, epithelial, and endothelial cells in response to IFN-γ and pro-inflammatory stimuli.
CXCL10 signals through the G protein-coupled receptor CXCR3, expressed on activated T cells, and plays an important role in T-cell migration during Th1 responses. It also inhibits angiogenesis and tumor growth and modulates adhesion molecule expression. Elevated CXCL10 levels are associated with allergic inflammation, infections, and Alzheimer’s disease.
A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number can range from 10⁵ to 10⁸ cells/test, determined empirically.
Target Information
IP-10 (interferon-gamma induced protein 10 kD; in mouse, cytokine responsive gene 2 or mob-1) belongs to the CXC chemokine superfamily. It stimulates monocyte, NK cell, and T-cell migration, regulates T-cell and progenitor maturation, modulates adhesion molecule expression, and inhibits angiogenesis. IP-10 and Mig share the same receptor, CXCR3.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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