Thermo Fisher Scientific CENPJ Polyclonal Antibody

Applications

Immunocytochemistry (ICC/IF)

• Tested Dilution: 0.25–2 µg/mL
• Publications: (정보 없음)

Product Specifications

Product Specific Information

• Immunogen sequence:
  SNILSHEQSN FCRTAHGDFV LTSKRASPNL FSEAQYQEAP VEKNNLKEEN RNHPTGESIL CWEKVTEQIQ EANDKNLQKH DDSSEVANIE ERPIKAAIG

• Antigen sequence identity:
  Mouse 61%; Rat 61%

Target Information

This gene encodes a protein belonging to the centromere protein family. During cell division, it plays a structural role in maintaining centrosome integrity and normal spindle morphology, and is involved in microtubule disassembly at the centrosome.
It functions as a transcriptional coactivator in the Stat5 signaling pathway and also as a coactivator of NF-kappaB-mediated transcription, likely via interaction with p300/CREB-binding protein.
Mutations in this gene are associated with primary autosomal recessive microcephaly, characterized by severely reduced brain size and mental retardation.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.