Thermo Fisher Scientific TNN Polyclonal Antibody
Tenascin-N 단백질을 인식하는 Rabbit Polyclonal Antibody로, Human, Mouse, Rat에 반응합니다. Western Blot 및 Immunocytochemistry에 적합하며, 액상 형태로 1 mg/mL 농도입니다. Affinity chromatography로 정제되어 연구용으로 사용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
- Publications: References
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:500
- Publications: References
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human TNN (Accession Q9UQP3), corresponding to amino acid residues H1229–Y1279 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2900654 |
Product Specific Information
Antibody detects endogenous levels of total Tenascin-N.
Target Information
Extracellular matrix protein that seems to be a ligand for ITGA8:ITGB1, ITGAV:ITGB1 and ITGA4:ITGB1 (PubMed:17909022).
Involved in neurite outgrowth and cell migration in hippocampal explants.
During endochondral bone formation, inhibits proliferation and differentiation of proteoblasts mediated by canonical WNT signaling.
In tumors, stimulates angiogenesis by elongation, migration and sprouting of endothelial cells (PubMed:19884327).
Expressed in most mammary tumors, may facilitate tumorigenesis by supporting the migratory behavior of breast cancer cells (PubMed:17909022).
[UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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