
Thermo Fisher Scientific IRAK-M Polyclonal Antibody
IRAK-M 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 Immunocytochemistry에 적합. 항원 친화 크로마토그래피로 정제된 액상 항체로, 인간 반응성. 단기 4°C, 장기 -20°C 보관 권장.
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Thermo Fisher Scientific IRAK-M Polyclonal Antibody
Applications and Tested Dilution
- Western Blot (WB): 1:500–1:3,000
- Immunocytochemistry (ICC/IF): 1:100–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 58–357 of IRAK3 (Uniprot ID: Q9Y616) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.22 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.1M Tris glycine, pH 7, with 10% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_11153735 |
Product Specific Information
- Recommended positive controls: DDDDK-tagged IRAK3-transfected 293T cells
- Predicted reactivity: Mouse (80%), Bovine (84%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
IRAK3 (Interleukin-1 receptor-associated kinase 3) is a serine/threonine kinase and a member of the IRAK family, essential for Toll/IL-R immune signaling pathways. It is primarily expressed in monocytes and macrophages and acts as a negative regulator of Toll-like receptor signaling. IRAK3 plays a role in innate immunity and is associated with susceptibility to asthma and immunocompromised states during sepsis.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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