
Thermo Fisher Scientific NFkB p100 Recombinant Rabbit Monoclonal Antibody (SAIC-26C-15)
인간 NFKB2(NFkB p100)를 인식하는 재조합 토끼 단클론 항체. ICC/IF 및 질량 분석에 사용 가능하며, 고순도의 Protein A 정제 항체. 단기 4°C, 장기 -20°C 보관 권장. 연구용으로만 사용.
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Applications
| Application | Tested Dilution |
|---|---|
| Immunocytochemistry (ICC/IF) | 10 µg/mL |
| Mass Spectrometry (MS) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | SAIC-26C-15 |
| Immunogen | Peptide IEVDLVTHSDPPR derived from the transcription factor NFKB2 (NF-kappa-B p100 subunit) conjugated to KLH |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage buffer | PBS |
| Contains | 0.02% ProClin 300 |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_3074350 |
Product Specific Information
Specificity: Recognises human NFKB2.
Target Information
This gene encodes a subunit of the transcription factor complex nuclear factor-kappa-B (NFkB). The NFkB complex is expressed in numerous cell types and functions as a central activator of genes involved in inflammation and immune function. The protein encoded by this gene can function as both a transcriptional activator or repressor depending on its dimerization partner. The p100 full-length protein is co-translationally processed into a p52 active form. Chromosomal rearrangements and translocations of this locus have been observed in B cell lymphomas, some of which may result in the formation of fusion proteins. There is a pseudogene for this gene on chromosome 18. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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