
Thermo Fisher Scientific TIMM8A Monoclonal Antibody (2F11)
Human TIMM8A 단백질을 인식하는 Mouse monoclonal antibody (Clone 2F11). Western blot, IHC, ELISA 등에 사용 가능. Affinity chromatography로 정제된 액상 형태로 제공되며, PBS buffer에 보존제 없이 포함. -20°C에서 보관.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 3 µg/mL |
| ELISA | 0.3 ng/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 2F11 |
| Immunogen | TIMM8A (NP_004076, 9–97 a.a.) partial recombinant protein with GST tag (GST MW: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
AAGLGAVDPQ LQHFIEVETQ KQRFQQLVHQ MTELCWEKCM DKPGPKLDSR AEACFVNCVE RFIDTSQFIL NRLEQTQKSK PVFSESLSD
Target Information
Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects hydrophobic precursors from aggregation and guides them through the mitochondrial intermembrane space. The TIMM8-TIMM13 complex mediates the import of proteins such as TIMM23, SLC25A12/ARALAR1, and SLC25A13/ARALAR2, while the predominant TIMM9-TIMM10 70 kDa complex mediates the import of additional proteins. Probably necessary for normal neurologic development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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