Thermo Fisher Scientific WDR74 Monoclonal Antibody (OTI4F2)
WDR74 단백질을 인식하는 Mouse IgG1 단클론 항체로 Western blot에 적합합니다. 인간, 마우스, 랫트 등 다양한 종에 반응하며, 고순도 친화 크로마토그래피로 정제되었습니다. PBS 기반 완충액에 안정화되어 -20°C에서 보관 가능합니다.
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Applications
- Western Blot (WB)
Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Dog, Human, Mouse, Non-human primate, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4F2 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 114–385 of WDR74 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2723783 |
Target Information
The yeast nucleolar protein NOP7 is necessary for the maturation of 66S preribosomes and interacts with numerous other proteins. One such protein is an essential, conserved WD repeat protein, NOP seven-associated protein 1 (NSA1), that is also required for the yeast 66S ribosome assembly. NSA1 is also associated with the AAA ATPase Rix7, and release of NSA1 from a novel late nucleolar pre-60S requires the Rix7 function. NSA1 has also been found upregulated in mammalian cancer cells, suggesting it may also play a role in cell proliferation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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