Thermo Fisher Scientific MMACHC Polyclonal Antibody
Human MMACHC 단백질을 인식하는 Rabbit Polyclonal 항체로, WB 및 IHC(P)에서 검증됨. 항원 친화 크로마토그래피로 정제되었으며, PBS/glycerol buffer에 보관. 비타민 B12 대사 관련 연구용으로 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human MMACHC. Recombinant protein control fragment (Product #RP-94200). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2644011 |
Product Specific Information
Immunogen sequence:
EIIADYEVHP NRRPKILAQT AAHVAGAAYY YQRQDVEADP WGNQRISGVC IHPRFGGWFA IRGVVLLPGI EVPDLPPRKP HDCVPT
Highest antigen sequence identity to the following orthologs:
- Mouse: 91%
- Rat: 90%
Target Information
The exact function of the MMACHC protein is not known, however, its C-terminal region shows similarity to TonB, a bacterial protein involved in energy transduction for cobalamin (vitamin B12) uptake. It is postulated that this protein may have a role in the binding and intracellular trafficking of cobalamin. Mutations in this gene are associated with methylmalonic aciduria and homocystinuria type cblC.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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