Thermo Fisher Scientific Ezrin Recombinant Rabbit Monoclonal Antibody (037)

Applications

• Immunohistochemistry (Paraffin) (IHC (P)): 1:100–1:500

Product Specifications

Product Specific Information

This product is preservative-free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).

Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The antibody DNA sequences from immunoreactive rabbits are cloned and expressed in host cells. Individual clones are screened to select the best candidates for production.

Advantages of recombinant rabbit monoclonal antibodies include:

• Better specificity and sensitivity
• Lot-to-lot consistency
• Animal origin-free formulations
• Broader immunoreactivity due to the large rabbit immune repertoire

This antibody has specificity for Human Ezrin/villin 2.

Target Information

Ezrin is a cytoplasmic peripheral membrane protein functioning as a protein-tyrosine kinase substrate in microvilli. As a member of the ERM protein family, it acts as a linker between the plasma membrane and the actin cytoskeleton. Ezrin plays a critical role in cell surface structure adhesion, migration, and organization, and has been implicated in various human cancers. A pseudogene on chromosome 3 and alternatively spliced variants have been identified.

For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.