Thermo Fisher Scientific KCNT2 Polyclonal Antibody
KCNT2 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, IHC, Flow cytometry에 사용 가능. Human 종에 반응하며, 고순도 Protein A 및 항원 친화 크로마토그래피로 정제됨. 연구용으로만 사용.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:100 |
| Flow Cytometry (Flow) | 1:10–1:50 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide between 1069–1097 amino acids from the C-terminal region of human KCNT2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2541355 |
Target Information
Kcnt2 calcium (Ca²⁺)-activated potassium channels (KCa) are a group of 6/7-TM ion channels that selectively transport K⁺ ions across biological membranes. KCa channels are classified into three subtypes: SK, IK, and BK channels (small, intermediate, and big conductance).
Kcnt2 is an outward rectifying potassium channel producing rapidly activating outward rectifier K⁺ currents. It is activated by high intracellular sodium and chloride levels and inhibited by ATP and inhalation anesthetics such as isoflurane.
Functionally, Kcnt2 is inhibited upon stimulation of G-protein coupled receptors such as CHRM1 and GRIA1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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