
Thermo Fisher Scientific Phospho-Hsp27 (Ser78) Monoclonal Antibody (5E1)
Phospho-Hsp27 (Ser78) 단백질을 표적하는 Rabbit Monoclonal Antibody (Clone 5E1). Western blot 및 Immunocytochemistry에 적합. 액상 형태로 1 mg/mL 농도, -20°C 보관. 세포 스트레스 반응 및 단백질 접힘 연구용.
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Applications
- Western Blot (WB): 1:1,000
- Immunocytochemistry (ICC/IF): 1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 5E1 |
| Immunogen | Synthetic peptide derived from human Hsp27 (S78), around 50-100aa (phospho S78) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
Target Information
Cells respond to environmental stress by increasing expression of heat shock or stress proteins. HSPB1 (Hsp27) is a small heat shock protein acting as a molecular chaperone, maintaining denatured proteins in a folding-competent state. It contributes to stress resistance and actin organization.
HSP27 regulates phosphorylation and axonal transport of neurofilament proteins. Mutations in this gene are associated with Charcot-Marie-Tooth disease 2F and Neuronopathy distal hereditary motor 2B.
For Research Use Only.
Not for use in diagnostic procedures or resale without express authorization.
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