Thermo Fisher Scientific YARS Polyclonal Antibody

Applications and Tested Dilution

Product Specifications

Product Specific Information

Immunogen sequence:

SKEYTLDVYR LSSVVTQHDS KKAGAEVVKQ VEHPLLSGLL YPGLQALDEE 
YLKVDAQFGG IDQRKIFTFA EKYLPALGYS KRVHLMNPMV PGLTGSKMSS 
SEEESKIDLL DRKEDVKK

Target Information

Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Tyrosyl-tRNA synthetase belongs to the class I tRNA synthetase family. Cytokine activities have also been observed for the human tyrosyl-tRNA synthetase, after it is split into two parts, an N-terminal fragment that harbors the catalytic site and a C-terminal fragment found only in the mammalian enzyme. The N-terminal fragment is an interleukin-8-like cytokine, whereas the released C-terminal fragment is an EMAP II-like cytokine.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.