Thermo Fisher Scientific MX2 Polyclonal Antibody
MX2 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, IHC(P), ICC/IF에 사용 가능. 인간 및 마우스 시료에 반응하며, 고순도 Affinity chromatography 정제. PBS/glycerol buffer에 보관하며 -20°C에서 안정적. 연구용으로 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human MX2 (Accession P20592), corresponding to amino acid residues E372–L422 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2851437 |
Product Specific Information
Antibody detects endogenous levels of total MX2.
Target Information
Members of the Dynamin family include GTPase, microtubule-associated proteins involved in cellular trafficking, including microtubule bundling and endocytosis.
Mx1 (MxA) is an interferon (IFN)-induced protein resistant to influenza A virus and vesicular stomatitis virus (VSV), suggesting an antiviral role.
Mx1 shares 63% identity with Mx2 (MxB), which lacks antiviral activity. Mx2 is localized at the cytoplasmic face of nuclear pores and is not interferon-dependent. It may regulate nuclear import efficiency or kinetics, a function related to its antiviral relatives.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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